Research & Technology

Research and education is a major part of Mr Jeremy Crane's ongoing commitment to vascular and transplant surgery. He has been invited to lecture at surgical conferences both nationally and internationally (France, Israel, USA) including, St George's Vascular Access Course, Charing Cross Symposium, UK Pancreas Transplant Forum, London Transplant Surgery Symposia.

Geometry and haemodynamics - 3D reconstruction of blood vessels to work out how blood flow affects disease (atherosclerosis/myointimal hyperplasia) in blood vessels is an ongoing research interest.

Vascular access surgery - ongoing work on a large prospective and retrospective audit study into improving UK outcomes for vascular access arteriovenous fistula operations for haemodialysis.


MD Postgraduate Thesis

Mr Jeremy Crane's Imperial College award-winning MD project was researched at a clinical/scientific interface within the fascinating fields of biotechnology and aeronautical engineering. He took two years out of clinical surgery, in the hiatus between senior house officer and specialist registrar posts.  His thesis supervisors were Professor Colin Caro and Professor Nick Cheshire.

Haemodynamics (the flow of blood) is governed by blood vessel geometry, which influences development of myointimal hyperplasia (MIH) and atheroma. Interest has arisen in the geometry at sites susceptible to disease. One such site is the distal anastomosis of bypass grafts, the focus of my thesis. It contributed to original literature by classifying in vivo geometry of infra-inguinal vein graft distal anastomoses using a proprietary magnetic resonance imaging 3D reconstruction technique. Also using MRI, aortic bifurcations in healthy subjects were studied and animal ex vivo studies were examined to identify the effect of three-dimensionality within a bypass graft.

His research was presented at the European Society of Vascular Surgery 2004, winning first prize in the Young Vascular Surgeon's session.